Title of article
Structure based design: Novel spirocyclic ethers as nonpeptidal P2-ligands for HIV protease inhibitors
Author/Authors
Arun K. Ghosh، نويسنده , , K. Krishnan، نويسنده , , D. Eric Walters، نويسنده , , Wonhwa Cho، نويسنده , , Hanna Cho، نويسنده , , Yumee Koo، نويسنده , , Jose Trevino، نويسنده , , Louis Holland، نويسنده , , Jim Buthod، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
4
From page
979
To page
982
Abstract
A series of novel spirocyclic ethers were designed to function as nonpeptidal P2-ligands for HIV-1 protease inhibitors. Incorporation of designed ligands in the (R)-(hydroxyethylamino)sulfonamide isostere afforded potent HIV protease inhibitors.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789360
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