Title of article
Design and synthesis of bio-isosteres of thymidine triphosphate
Author/Authors
Alastair O. Goldring، نويسنده , , Jan Balzarini، نويسنده , , Ian H. Gilbert، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
4
From page
1211
To page
1214
Abstract
This paper describes the design and synthesis of potential isosteres of triphosphates which should show enhanced metabolic stability and lipophilicity compared to triphosphates. The triphosphate isosteres were then linked to nucleosides and evaluated for their inhibitory activity against HIV infection.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789405
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