Title of article
3-Trifluoromethylcarbacephems: Synthesis of broad spectrum antibacterial compounds
Author/Authors
G. K. Cook، نويسنده , , W. J. Hornback، نويسنده , , J. H. McDonald III، نويسنده , , J. E. Munroe، نويسنده , , N. J. Snyder، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
1261
To page
1266
Abstract
The enhanced stability of the carbacephem nucleus over the corresponding cephalosporin nucleus has allowed the synthesis of 7-arylglycyl-3-trifluoromethyl-carbacephems. These unique carbacephems possess broad spectrum activity and high stability to both plasmid and chromosomally mediated ß-lactamases.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789414
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