Title of article :
Anti-AIDS agents. 32.1 synthesis and anti-HIV activity of betulin derivatives
Author/Authors :
I-Chen Sun، نويسنده , , Jing-Kang Shen، نويسنده , , Hui-Kang Wang، نويسنده , , L. Mark Cosentino، نويسنده , , Kuo-Hsiung Lee، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Abstract :
Eleven betulin derivatives were prepared and evaluated for anti-HIV activity in H9 lymphocytes. Compound 4 was found to be the most active with EC50 and TI of 0.00066 μM and 21,515, respectively.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters