Sulfonamide derivatives of benzylamine block cholesterol biosynthesis in HepG2 cells: A new type of potent squalene epoxidase inhibitors
Author/Authors :
J. -P. Gotteland، نويسنده , , C. Loubat، نويسنده , , B. Planty، نويسنده , , D. Junquero، نويسنده , , A. Delhon، نويسنده , , S. Halazy ، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Pages :
6
From page :
1337
To page :
1342
Abstract :
Sulfonamide derivatives of ene-yne benzylamine 1 have been prepared and identified as a new class of potent SE inhibitors having demonstrated activity in HepG2 cells as cholesterol biosynthesis inhibitors.
