Title of article
Synthesis and biological evaluation of new tetrahydronaphthalene derivatives as thromboxane receptor antagonists
Author/Authors
Bernard Cimetière، نويسنده , , Thierry Dubuffet، نويسنده , , Olivier Muller، نويسنده , , Jean-Jacques Descombes، نويسنده , , Serge Simonet، نويسنده , , Michel Laubie، نويسنده , , Tony J. Verbeuren، نويسنده , , Gilbert Lavielle، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
1375
To page
1380
Abstract
New polysubstituted tetrahydronaphthalene derivatives were prepared as thromboxane receptor (TP-receptor) antagonists. Within this series of compounds S 18886 has been identified as an orally active, highly potent antagonist with a very long duration of action in different species.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789437
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