Author/Authors :
Bernard Cimetière، نويسنده , , Thierry Dubuffet، نويسنده , , Olivier Muller، نويسنده , , Jean-Jacques Descombes، نويسنده , , Serge Simonet، نويسنده , , Michel Laubie، نويسنده , , Tony J. Verbeuren، نويسنده , , Gilbert Lavielle، نويسنده ,
Abstract :
New polysubstituted tetrahydronaphthalene derivatives were prepared as thromboxane receptor (TP-receptor) antagonists. Within this series of compounds S 18886 has been identified as an orally active, highly potent antagonist with a very long duration of action in different species.
