Title of article
Novel constrained CCK-B dipeptoid antagonists derived from pipecolic acid
Author/Authors
Bruno Bellier، نويسنده , , Sophie Da Nascimento، نويسنده , , Hervé Meudal، نويسنده , , Edith Gincel، نويسنده , , Bernard P. Roques، نويسنده , , Christiane Garbay، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
1419
To page
1424
Abstract
A new series of 4-substituted pipecolic acid derivatives was prepared and incorporated into dipeptoids. The resulting products behave as moderately potent CCK-B antagonists but their constrained structure and its comparison with structurally related compounds yield valuable information about the conformational requirements for optimal recognition of the CCK-B receptor by antagonists.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789445
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