Title of article :
A potent dipeptide inhibitor of dipeptidyl peptidase IV
Author/Authors :
Masaki Yamada، نويسنده , , Chieko Okagaki، نويسنده , , Takanori Higashijima، نويسنده , , Sumiko Tanaka، نويسنده , , Tetsuo Ohnuki، نويسنده , , Takahisa Sugita، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Abstract :
A series of novel potent inhibitors of dipeptidyl peptidase IV (DPP-IV) has been developed. A brief structure-activity relationship of the inhibitors was investigated. The dipeptide TSL-225, tryptophyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, was identified with the critical structure for the inhibitory activity.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
