Title of article :
Adenosine deaminase inhibitors. Synthesis and biological evaluation of aralkyladenines (ARADS)
Author/Authors :
Mark A. Curtis، نويسنده , , Vaibhav Varkhedkar، نويسنده , , Palle V. P. Pragnacharyulu، نويسنده , , Elie Abushanab، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Abstract :
Several 9-aralkyladenines have been prepared and their ADA inhibitory activity was determined. A minimum of two carbon atoms separating the aromatic ring from the adenine-bearing carbon (C3′) was found essential for potent activity.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters