Title of article
Solution and solid phase combinatorial synthesis of peptidomimetic library containing diversified α-methylated amino acids
Author/Authors
Sang Woong Kim، نويسنده , , You Seung Shin، نويسنده , , Seonggu Ro، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
4
From page
1665
To page
1668
Abstract
A combinatorial peptidomimetic library containing diversified α-methylated amino acids was generated by the Ugi four component condensation (4cc) reaction from acids, amines, isocyanides and ketones in both solution and solid phase synthetic procedures. This one-pot methodology overall gave fair to good yields, which compare well with multi-step syntheses.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789492
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