Author/Authors :
Robert L. Hudkins، نويسنده , , Mohamed Iqbal، نويسنده , , Chung-Ho Park، نويسنده , , Joel Goldstein، نويسنده , , Joseph L. Herman، نويسنده , , Efraim Shek، نويسنده , , Chikara Murakata، نويسنده , , John P. Mallamo، نويسنده ,
Abstract :
Prodrug esters of the indolocarbazole CEP-751 (KT-6587) were prepared with the goal of identifying water soluble, stable but cleavable forms for intravenous dosing. A dipeptide proform Lys-β-Ala (16, CEP-2563/KT-8391) was identified for advancement to clinical trials.
