Author/Authors :
Michael Arlt، نويسنده , , Henning B?ttcher، نويسنده , , Angelika Riethmüller، نويسنده , , Günter Schneider، نويسنده , , Gerd D. Bartoszyk، نويسنده , , Hartmut Greiner، نويسنده , , Christoph A. Seyfried، نويسنده ,
Abstract :
SAR for a novel series of dopamine D4 receptor ligands is shown. Very selective, highly potent compounds like 1-(2-pyrimidinyl)-4-(3-thienyl)-benzyl)-piperazine (5f) and 2-(4-(1-fluorenylmethyl)-1-piperazinyl)-pyrimidine (8c) were obtained.
