Title of article :
Synthesis of novel substituted pyridines as inhibitors of endothelin coverting enzyme-1 (ECE-1)
Author/Authors :
Mark A. Massa، نويسنده , , William C. Patt، نويسنده , , Kyunghye Ahn، نويسنده , , Andre M. Sisneros، نويسنده , , Sarah B. Herman، نويسنده , , Annette Doherty، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Pages :
6
From page :
2117
To page :
2122
Abstract :
A series of bi-aryl pyridine carboxylic acids has been prepared and evaluated as inhibitors of ECE-1. The analogs were prepared by Pd catalyzed cross couplings of halogenated pyridines with heteroaryl organo-boranes, -tinate or -zincate derivatives.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
1998
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
789581
Link To Document :
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