• Title of article

    A dipyrido [2,3-b:3′,2′-f]azepine analog of the HIV-1 reverse transcriptase inhibitor nevirapine

  • Author/Authors

    Alexey B. Dyatkin، نويسنده , , Janice R. Brickwood، نويسنده , , John R. Proudfoot، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1998
  • Pages
    4
  • From page
    2169
  • To page
    2172
  • Abstract
    The syntheses of 11-ethyl and 11-cyclopropyldipyrido[2,3-b:3′,2′-f]azepines, analogs of the HIV-1 reverse transcriptase inhibitor nevirapine 1, are described. These compounds exhibit potency equivalent to nevirapine in the inhibition of wild-type and some mutant RT enzymes.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1998
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    789591