Title of article :
Construction of a family of biphenyl combinatorial libraries: Structure-activity studies utilizing libraries of mixtures
Author/Authors :
Bernard R. Neustadt، نويسنده , , Elizabeth M. Smith، نويسنده , , Neil Lindo، نويسنده , , Terry Nechuta، نويسنده , , Alan Bronnenkant، نويسنده , , Arthur Wu، نويسنده , , Lydia Armstrong، نويسنده , , N. Chandra Kumar، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Pages :
4
From page :
2395
To page :
2398
Abstract :
A set of biphenyl aminoacid building blocks has been synthesized. These were used to construct partially-peptidic combinatorial libraries as equimolar multi-component samples. Activity of members of this library as vitronectin receptor antagonists is described, together with SAR studies of the most active members. These studies illustrate several important features of combinatorial libraries.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
1998
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
789632
Link To Document :
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