Author/Authors :
Bernard R. Neustadt، نويسنده , , Elizabeth M. Smith، نويسنده , , Neil Lindo، نويسنده , , Terry Nechuta، نويسنده , , Alan Bronnenkant، نويسنده , , Arthur Wu، نويسنده , , Lydia Armstrong، نويسنده , , N. Chandra Kumar، نويسنده ,
Abstract :
A set of biphenyl aminoacid building blocks has been synthesized. These were used to construct partially-peptidic combinatorial libraries as equimolar multi-component samples. Activity of members of this library as vitronectin receptor antagonists is described, together with SAR studies of the most active members. These studies illustrate several important features of combinatorial libraries.