Title of article
Construction of a family of biphenyl combinatorial libraries: Structure-activity studies utilizing libraries of mixtures
Author/Authors
Bernard R. Neustadt، نويسنده , , Elizabeth M. Smith، نويسنده , , Neil Lindo، نويسنده , , Terry Nechuta، نويسنده , , Alan Bronnenkant، نويسنده , , Arthur Wu، نويسنده , , Lydia Armstrong، نويسنده , , N. Chandra Kumar، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
4
From page
2395
To page
2398
Abstract
A set of biphenyl aminoacid building blocks has been synthesized. These were used to construct partially-peptidic combinatorial libraries as equimolar multi-component samples. Activity of members of this library as vitronectin receptor antagonists is described, together with SAR studies of the most active members. These studies illustrate several important features of combinatorial libraries.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789632
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