• Title of article

    Two novel oleanolic acid saponins having a sialyl Lewis X mimetic structure from Achyranthes fauriei root

  • Author/Authors

    Yoshiteru Ida، نويسنده , , Yohko Satoh، نويسنده , , Masumi Katsumata، نويسنده , , Miki Nagasao، نويسنده , , Yasuaki Hirai، نويسنده , , Tetsuya Kajimoto، نويسنده , , Naho Katada، نويسنده , , Masako Yasuda، نويسنده , , Toshinori Yamamoto، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1998
  • Pages
    4
  • From page
    2555
  • To page
    2558
  • Abstract
    Two novel triterpene glycosides, achyranthosides E and F, were isolated as methyl esters from the root of Achyranthes fauriei, an antiinflammatory medicinal plant. Their structures were characterized as oleanolic acid glucuronides having unique substituents composed of C6H9O5 and C9H15O7, respectively, at the C-3 position of glucuronic acid. These compounds are active components which can inhibit the excess recruiting of neutrophiles to injured tissues 1,000 times more potently than sialyl Lewis X.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1998
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    789663