Title of article
Synthesis and properties of prodrugs activated in hypoxia to give bleomycin analogues
Author/Authors
Jackie A. Highfield، نويسنده , , Lina K. Mehta، نويسنده , , John Parrick، نويسنده , , Luis P. Candeias، نويسنده , , Peter Wardman، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
2609
To page
2614
Abstract
Prodrugs bioreductively activated to bleomycin analogues are reported. The production of hydroxyl radicals in the presence of Fe(II) and dioxygen by both the prodrugs and the activated products are determined and their in vitro cytotoxicity measured.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789674
Link To Document