Author/Authors :
Julio C. Medina، نويسنده , , Bei Shan and Nigel P.C. Walker، نويسنده , , Holger Beckmann، نويسنده , , Robert P. Farrell، نويسنده , , David L. Clark، نويسنده , , R. Marc Learned، نويسنده , , Daniel Roche، نويسنده , , Angela Li Kwang Wee، نويسنده , , Vijay Baichwal، نويسنده , , Casey Case، نويسنده , , Patrick A. Baeuerle، نويسنده , , Terry Rosen، نويسنده , , Juan C. Jaen، نويسنده ,
Abstract :
A novel series of pentafluorobenzenesulfonamides has been shown to inhibit the growth of a variety of human tumor cell lines. Among the cell types against which these agents were evaluated were the multidrug resistant (MDR) cell lines MCF-7/ADR and P388/ADR. The cytotoxic activity of members of this series of compounds was not affected by the multidrug resistant pump in MCF-7/ADR or P388/ADR cells.
