Title of article
Reversal of multidrug resistance (MDR) by aspidofractinine-type indole alkaloids
Author/Authors
Toh-Seok Kam، نويسنده , , G. Subramaniam، نويسنده , , Kooi-Mow Sim، نويسنده , , K. Yoganathan، نويسنده , , Takashi Koyano، نويسنده , , Mitsuhide Toyoshima، نويسنده , , Mun-Chual Rho، نويسنده , , Masahiko Hayashi، نويسنده , , Kanki Komiyama، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
4
From page
2769
To page
2772
Abstract
A series of indole alkaloids of the aspidofractinine-type was assessed for their potential in reversing MDR in vincristine-resistant KB cells. Of the compounds tested, kopsiflorine, kopsamine, pleiocarpine, 11-methoxykopsilongine, lahadinine A and N-methoxycarbonyl-11,12-methylenedioxy-Δ16,17-kopsinine were found to show appreciable activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789703
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