A stereoselective α-fucosylation reaction using 1-hydroxy donor for the practical synthesis of selectin blocker

A 1-hydroxy donor affords a high stereoselectivity of glycosylation in the presence of TMSOTf and is a very useful substrate for the preparation of an α-L-fucosyl dipeptide in a stereoselective manner. The donor will be a key component in the preparation of an attractively biological selectin blocker 1.