Title of article :
Identification of a series of 1,2,3,4-tetrahydroisoquinolinyl- benzamides with potential anticonvulsant activity
Author/Authors :
Wai N. Chan، نويسنده , , Michael S. Hadley، نويسنده , , John D. Harling، نويسنده , , Hugh J. Herdon، نويسنده , , Jeffrey C. Jerman، نويسنده , , Barry S. Orlek، نويسنده , , Tania O. Stean، نويسنده , , Mervyn Thompson، نويسنده , , Neil Upton، نويسنده , , Robert W. Ward، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Pages :
4
From page :
2903
To page :
2906
Abstract :
A series of N-(tetrahydroisoquinolinyl)-2-methoxybenzamides was identified by high-throughput screening at the novel SB-204269 binding site. SAR studies have provided compounds 4 and 14 with high affinity and good anticonvulsant activity in animal models.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
1998
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
789729
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=789729
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