Title of article
Synthesis and evaluation of artificial taxoids with antitumor and multi-drug resistance reversing activities
Author/Authors
Koichiro Morihira، نويسنده , , Toshiyuki Nishimori، نويسنده , , Hiroyuki Kusama، نويسنده , , Yoshiaki Horiguchi، نويسنده , , Isao Kuwajima، نويسنده , , Takashi Tsuruo، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
2977
To page
2982
Abstract
Artificial taxoids were synthesized and subjected to evaluation of their ability of multi-drug resistance reversing and antitumor activities. While the taxoid 4 could not increase cellular accumulation of vincristine in multi-drug resistant tumor cells, the C4-hydroxy analog 15 showed significant effect. However, these compounds showed weak activities on growth inhibition of cancer cells.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789742
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