Title of article :
Rational design of a new series of mixed anti-HIV pronucleotides
Author/Authors :
Nathalie Schlienger، نويسنده , , Thierry Beltran، نويسنده , , Christian Perigaud، نويسنده , , Isabelle Lefebvre، نويسنده , , Alain Pompon، نويسنده , , Anne-Marie Aubertin، نويسنده , , Gilles Gosselin، نويسنده , , Jean-Louis Imbach، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Pages :
4
From page :
3003
To page :
3006
Abstract :
MonoSATE aryl phosphotriesters of AZT are able to deliver intracellularly the corresponding 5′-mononucleotide. This process requires activation by an esterase followed by a phosphodiesterase. This finding opens the way to the design of new pronucleotide series.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
1998
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
789748
Link To Document :
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