• Title of article

    Synthesis and evaluation of paclitaxel C7 derivatives: Solution phase synthesis of combinatorial libraries

  • Author/Authors

    Laxminarayan Bhat، نويسنده , , Yanbin Liu، نويسنده , , Sam F. Victory، نويسنده , , Richard H. Himes، نويسنده , , Gunda I. Georg، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1998
  • Pages
    6
  • From page
    3181
  • To page
    3186
  • Abstract
    A novel and efficient two-step, automated solution phase synthesis of a 26-membered combinatorial chemistry library of paclitaxel C7 esters was accomplished using the HP 7686 Solution Phase Synthesizer. Results of combinatorial synthesis, purification, analysis, and biological evaluation are described.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1998
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    789783