Title of article
Synthesis and evaluation of paclitaxel C7 derivatives: Solution phase synthesis of combinatorial libraries
Author/Authors
Laxminarayan Bhat، نويسنده , , Yanbin Liu، نويسنده , , Sam F. Victory، نويسنده , , Richard H. Himes، نويسنده , , Gunda I. Georg، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
3181
To page
3186
Abstract
A novel and efficient two-step, automated solution phase synthesis of a 26-membered combinatorial chemistry library of paclitaxel C7 esters was accomplished using the HP 7686 Solution Phase Synthesizer. Results of combinatorial synthesis, purification, analysis, and biological evaluation are described.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789783
Link To Document