Author/Authors :
Concepci?n P. Melero، نويسنده , , Luis G. Sevillano، نويسنده , , Esther Caballero، نويسنده , , Fernando Tomé، نويسنده , , Rosal?a Carr?n، نويسنده , , M. José Montero، نويسنده , , Arturo San Feliciano، نويسنده , , Manuel Medarde، نويسنده ,
Abstract :
The synthesis and inotropic activity of two families of hydroindenic compounds are described. Among them, a bis-guanylhydrazone derivative has demonstrated to produce an interesting positive inotropic effect on guinea pig atria, displaying at higher dosis a similar effect to that elicited by digoxin.