Author/Authors :
Shu-Hui Chen، نويسنده , , Stanley Lin، نويسنده , , Ivan King، نويسنده , , Tracy Spinka، نويسنده , , Ginger E. Dutschman، نويسنده , , Elizabeth A. Gullen، نويسنده , , Yung-Chi Cheng، نويسنده , , Terrence W. Doyle، نويسنده ,
Abstract :
The synthesis of β-D-Fd4C was achieved in a stereoselective fashion from D-xylose. The antiviral activity and cytotoxicity of β-D-Fd4C was compared with that of β-L-Fd4C and 3TC (Lamivudine). Of the three agents compared, β-L-Fd4C was found to be the most potent antiviral agent.
