Author/Authors :
Mankil Jung، نويسنده , , Imju Ko، نويسنده , , Seokjoon Lee، نويسنده , , Sun-Ju Choi، نويسنده , , Byoung Hee Youn، نويسنده , , Soo Kie Kim and، نويسنده ,
Abstract :
A new series of labdane-related diterpenes have been synthesized from (−)-sclareol and assayed in vitro cytotoxicity against mouse and human cancer cells. A key intermediate, homodrimane and furanolabdane derivatives show good in vitro cytotoxicity comparable to those of mitomycin C and adriamycin.
