Title of article
Design and synthesis of new potent, silent 5-HT1A antagonists by covalent coupling of aminopropanol derivatives with selective serotonin reuptake inhibitors
Author/Authors
M. Perez، نويسنده , , P. J. Pauwels، نويسنده , , I. Pallard-Sigogneau، نويسنده , , C. Fourrier، نويسنده , , P. Chopin، نويسنده , , C. Palmier، نويسنده , , V. Colovray، نويسنده , , S. Halazy ، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
3423
To page
3428
Abstract
Hybrid molecules built up by covalent coupling of aminopropanol derivatives (especially pindolol) with antidepressant drugs like fluoxetine, paroxetine or milnacipran were found to be potent and silent 5-HT1A antagonists (KB< 1 nM for 7c and 9a).
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789830
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