Author/Authors :
John G. Ondeyka، نويسنده , , Robert A. Giacobbe، نويسنده , , Gerald F. Bills، نويسنده , , Cristina Cuadrillero، نويسنده , , Dennis Schmatz، نويسنده , , Michael A. Goetz، نويسنده , , Deborah L. Zink، نويسنده , , Sheo B. Singh، نويسنده ,
Abstract :
Coprophilin, a decalin pentanedienoic acid methyl ester, was isolated from an unidentified fungus by bioassay guided separation. It inhibited (MIC = 1.5 μM) the growth of Eimeria tenella in an in vitro assay. The isolation, structure elucidation, absolute stereochemistry and biology are described.
