Author/Authors :
Arjun H. Banskota، نويسنده , , Yasuhiro Tezuka، نويسنده , , Le Kim Phung، نويسنده , , Kim Qui Tran، نويسنده , , Ikuo Saiki، نويسنده , , Yoshihisa Miwa، نويسنده , , Tooru Taga، نويسنده , , Shigetoshi Kadota، نويسنده ,
Abstract :
Seven novel cycloartane-type triterpenes were isolated from Combretum quadrangulare, and their structures were elucidated on the basis of spectral analysis. All these compounds were tested for their cytotoxicity against murine colon 26-L5 carcinoma cells. Methyl quadrangularate B (2) and methyl quadrangularate D (4) exhibited potent cytotoxicity having ED50 values 9.54 and 5.42 μM, respectively.
