• Title of article

    O-(Fluoresceinylmethyl)hydroxylamine (OFMHA): A fluorescent reagent for detection of damaged nucleic acids

  • Author/Authors

    Maciej Adamczyk، نويسنده , , Phillip G. Mattingly، نويسنده , , Jeffrey A Moore، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1998
  • Pages
    4
  • From page
    3599
  • To page
    3602
  • Abstract
    5- and 6-O-(Fluoresceinylmethyl)hydroxylamine (OFMHA, 5a, b) were prepared from the corresponding bis-pivaloyl-protected hydroxymethylfluoresceins (1a, b) in 50–70% yield. The hydroxylamine derivatives reacted smoothly with the abasic sites present in acid/heat stressed calf thymus DNA.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1998
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    789863