• Title of article

    2,6,9-trisubstituted purines : Optimization towards highly potent and selective CDK1 inhibitors

  • Author/Authors

    Patricia Imbach، نويسنده , , Hans-Georg Capraro، نويسنده , , Pascal Furet، نويسنده , , Helmut Mett، نويسنده , , Thomas Meyer، نويسنده , , Jürg Zimmermann، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1999
  • Pages
    6
  • From page
    91
  • To page
    96
  • Abstract
    Novel 2,6,9-substituted purine derivatives represent a class of potent and selective inhibitors of CDK1/cyclinB. The synthesis, SAR and biological profile of selected compounds are described.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1999
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    789899