Resin-supported labeling reagents

Resin-supported fluorescein, coumarin, acridinium, and biotin active esters were prepared from a new N-hydroxysuccinimidyl resin in high yield. The active esters were used to prepare representative conjugates with estriol, thyroxine, phenytoin, and desipramine haptens without need for purification beyond removal of the spent resin.