• Title of article

    Manipulation of the C(22)-C(27) region of rapamycin: Stability issues and biological implications

  • Author/Authors

    Frances C. Nelson، نويسنده , , Shawn J. Stachel، نويسنده , , C. P. Eng، نويسنده , , Suren N. Sehgal، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1999
  • Pages
    6
  • From page
    295
  • To page
    300
  • Abstract
    A novel series of rapamycin derivatives with modifications in the C(22)-C(27) region has been prepared. These compounds are evaluated for their ability to prevent ring fragmentation while still retaining immunosuppressive capabilities.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1999
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    789941