Title of article
Novel Series of O-substituted 8-quinolines and 4-benzothiazoles as potent antagonists of the bradykinin B2 receptors
Author/Authors
Holger Heitsch، نويسنده , , Adalbert Wagner، نويسنده , , Bernward A. Sch?lkens، نويسنده , , Klaus Wirth، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
327
To page
332
Abstract
The synthesis and the SAR study of novel O-substituted 8-quinolines and 4-benzothiazoles as highly potent non-peptide bradykinin B2 receptor antagonists are described. Several members of this series of antagonists efficiently inhibited the BK-induced vasoconstriction on different isolated organ preparations.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789947
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