Title of article :
Synthesis and biological evaluation of 1α,24-dihydroxy-25-nitrovitamin D3
Author/Authors :
Jun-ichi Oshida، نويسنده , , Makoto Okamoto، نويسنده , , Seiichi Ishizuka، نويسنده , , Shizuo Azuma، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1999
Abstract :
1α,24(R)-Dihydroxy-25-nitrovitamin D31 and 1α,24(S)-dihydroxy-25-nitrovitamin D32 were synthesized using the palladium-catalyzed alkylative enyne cyclization reaction. Their biological properties were studied based on VDR binding affinity and HL-60 cell differentiation activity.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
