Title of article
Leucine-phenylalanine dipeptide-based N-mesyloxysuccinimides: Synthesis of all four stereoisomers and their assay against serine proteases
Author/Authors
Andrew D. Abell، نويسنده , , Mark D. Oldham، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
497
To page
500
Abstract
The four stereoisomers of 3-(N-acetylleucylamino)-3-benzyl-1-[(methylsulfonyl)oxy]succinimide have been prepared and shown to inhibit α-chymotrypsin and human neutrophil elastase. The structural and stereochemical features that affect the potency and selectivity of inhibition are discussed.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789977
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