Title of article
Stereoselective synthesis and receptor activity of conformationally defined retinoid X receptor selective ligands
Author/Authors
Vidyasagar Vuligonda، نويسنده , , Michael E. Garst، نويسنده , , Roshantha A. S. Chandraratna، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
589
To page
594
Abstract
Retinoid X Receptor (RXR) specific ligands are currently being investigated for the treatment of metabolic diseases such as type II diabetes. We report the synthesis of conformationally locked retinoids, which are potent RXR selective ligands, and the attempted synthesis of 9-cyclopropyl locked analogs of RA and 9-cis RA.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789999
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