• Title of article

    Biophysical and biochemical properties of oligodeoxynucleotides containing 4′-C- and 5′-C-substituted thymidines

  • Author/Authors

    Guangyi Wang، نويسنده , , Patrick J. Middleton، نويسنده , , Catherine Lin، نويسنده , , Zbigniew Pietrzkowski، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1999
  • Pages
    6
  • From page
    885
  • To page
    890
  • Abstract
    We have previously reported oligodeoxynucleotides (ODNs) containing 4′-C- and 5′-C-substituted thymidines, which demonstrated certain favorable biophysical and biochemical properties. In this communication, the hybridization and nuclease stability data of the ODNs along with their capability to induce RNase H activity are presented.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1999
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790056