Title of article
Synthesis and structure-activity relationship of potent bicyclic lactam thrombin inhibitors
Author/Authors
Benoit Bachand، نويسنده , , John DiMaio، نويسنده , , M. Arshad Siddiqui، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
913
To page
918
Abstract
A simple and versatile method for preparation of (D)-Phe-Pro peptidomimetic bicyclic thiazolidine lactams is presented. These bicyclic lactams have chemical diversity α to the lactam carbonyl and, when linked to electrophilic arginines, provide potent thrombin inhibitors.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790061
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