Title of article
Synthesis of a new fluorogenic substrate for the continuous assay of mammalian phosphoinositide-specific phospholipase C
Author/Authors
Aleksey V. Rukavishnikov، نويسنده , , Tatiana O. Zaikova، نويسنده , , G. Bruce Birrell، نويسنده , , John F. W. Keana، نويسنده , , O. Hayes Griffith، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
1133
To page
1136
Abstract
The synthesis of a fluorogenic substrate for mammalian phosphoinositide-specific phospholipase C is described. The substrate, based on the widely used fluorescein molecule, is a water-soluble substrate analog of phosphatidylinositol-4-phosphate. The fluorogenic substrate 2 is shown to be a sensitive substrate for human PI-PLC-δ 1 in a continuous assay.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790105
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