Author/Authors :
Rodrigo V. Devivar، نويسنده , , Steve L. Koontz، نويسنده , , William J. Peltier، نويسنده , , James E. Pearson، نويسنده , , Todd A. Guillory، نويسنده , , Jill D. Fabricant، نويسنده ,
Abstract :
An alternative solid support for oligonucleotide synthesis was developed by coupling a polymer colloid to a modified polyethylene filter disc. The functions on the polymer colloid not used for attachment to the surface were derivatized with a Jeffamine® diamine and loaded with appropriate deoxynucleoside succinates. The performance of this support system was evaluated and compared to existing resins.
