Title of article
S1319: A novel β2-adrenoceptor agonist from a marine sponge Dysidea sp.
Author/Authors
Hidefumi Suzuki، نويسنده , , Kazutoshi Shindo، نويسنده , , Akihiro Ueno، نويسنده , , Toru Miura، نويسنده , , Masao Takei، نويسنده , , Masayuki Sakakibara، نويسنده , , Hiromi Fukamachi، نويسنده , , Junichi Tanaka، نويسنده , , Tatsuo Higa، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
1361
To page
1364
Abstract
In the course of screening of potential leads for β2-receptor agonists, we found a novel β2-adrenoceptor selective agonist, S 1319, from a marine sponge Dysidea sp. The active compound was isolated and structurally characterized as 4-hydroxy-7-[1-(1-hydroxy-2-methylamino)ethyl]-1,3-benzothiazole-2(3H)-one, a new member of the β2-adrenoceptor agonist. This is the first example of a sponge-derived β2-adrenoceptor agonist.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790150
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