Title of article
Uncarinic acids: Phospholipase Cγ1 inhibitors from hooks of Uncaria rhynchophylla
Author/Authors
Ji Suk Lee، نويسنده , , Mi Young Yang، نويسنده , , Hosup Yeo، نويسنده , , Jinwoong Kim، نويسنده , , Hyun Sun Lee، نويسنده , , Jong Seog Ahn، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
1429
To page
1432
Abstract
Bioactivity-guided fractionation of the CHCl3 extract from hooks of Uncaria rhynchophylla led to the isolation of two triterpene esters, namely uncarinic acids A (1) and B (2). Their structures were established by spectroscopic and chemical methods. These compounds inhibited phospholipase Cγ1 with IC50 values of 35.66 and 44.55 μM, respectively.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790164
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