Title of article :
Synthesis of 25-aminosterols, new antifungal agents
Author/Authors :
P. Beuchet، نويسنده , , M. Dherbomez، نويسنده , , L. Elkiel، نويسنده , , G. Charles، نويسنده , , Y. Letourneux، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1999
Abstract :
25-aminolanostenol 1 and 25-aminocholesterol 2 were hemisynthesized from natural sterols and tested in vitro against Candida albicans. The biological activity of compound 1 was rather weak, whereas 2 exhibited in vitro antifungal activity with MIC value of 4 μM.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
