Title of article
Selective binding of bryostatin analogues to the cysteine rich domains of protein kinase C isozymes
Author/Authors
Paul A. Wender، نويسنده , , Blaise Lippa، نويسنده , , Cheol-Min Park، نويسنده , , Kazuhiro Irie، نويسنده , , Akifumi Nakahara، نويسنده , , Hajime Ohigashi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
1687
To page
1690
Abstract
Designed bryostatin analogues are assayed for binding affinity to individual cysteine rich domains of several protein kinase C (PKC) isozymes. These analogues exhibit significant selectivity for the PKCδ-C1B peptide in terms of absolute affinity and the PKCδ-C1A peptide in terms of relative affinity when compared to phorbol-12,13-dibutyrate.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790214
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