Title of article
Synthesis and evaluation of 1-position-modified inositol 1,4,5-trisphosphate analogs
Author/Authors
Takanari Inoue، نويسنده , , Kazuya Kikuchi، نويسنده , , Kenzo Hirose، نويسنده , , Masamitsu Iino، نويسنده , , Tetsuo Nagano، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
1697
To page
1702
Abstract
IP3 analogs were synthesized by the modification of phosphate at the 1-position, and their affinity for the IP3 receptor was analyzed by means of surface plasmon resonance measurements. Our results suggest that a hydrophobic and charged moiety linked to this position enhances the affinity for the IP3 receptor.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790216
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