Title of article :
Photoinduced cross-linking of RNA by cis-Rh(phen)2Cl2+ and cis-Rh(phen)(phi)Cl2+: A new family of light activatable nucleic acid cross-linking agents
Author/Authors :
Noor-Ul-Iman and Taj Mohammad Khan، نويسنده , , Chaoping Chen، نويسنده , , Peixuan Guo، نويسنده , , Harry Morrison، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1999
Abstract :
The metal complexes, cis-Rh(phen)2Cl2+ and its more hydrophobic analog cis-Rh(phen)(phi)Cl2+, have been shown to photocross-link the 120-base 29-encoded pRNA. Primer extension on the cis-Rh(phen)(phi)Cl2+-photocross-linked RNA revealed that guanines are responsible for the interstrand cross-links.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
