Title of article
5-fluoro-2-methyl-N-[5-(5H-pyrrolo[2,1-c][1,4]benzodiazepine-10(11H)-yl carbonyl)-2-pyridinyl]benzamide (CL-385004) and analogs as orally active arginine vasopressin receptor antagonists
Author/Authors
Venkatesan Aranapakam، نويسنده , , J. Donald Albright، نويسنده , , George T. Grosu، نويسنده , , Efren G. Delos Santos، نويسنده , , Peter S. Chan، نويسنده , , Joseph Coupet، نويسنده , , Xun Ru، نويسنده , , Trina Saunders، نويسنده , , H. Mazandarani، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
1737
To page
1740
Abstract
Synthesis and structure-activity relationships (SAR) of orally active arginine vasopressin (AVP) receptor antagonists are discussed. Potent and orally active AVP receptor antagonists are produced when ring A or VPA-985 (1) is replaced with a 3-pyridinyl unit (2).
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790223
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