• Title of article

    Design and synthesis of diaminopyrrolidinone inhibitors of human osteoclast cathepsin K

  • Author/Authors

    Kevin J. Duffy، نويسنده , , Lance H. Ridgers، نويسنده , , Renee L. DesJarlais، نويسنده , , Thaddeus A. Tomaszek، نويسنده , , Mary J. Bossard، نويسنده , , Scott K. Thompson، نويسنده , , Richard M. Keenan، نويسنده , , Daniel F. Veber، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1999
  • Pages
    4
  • From page
    1907
  • To page
    1910
  • Abstract
    The structure-based design and synthesis of lactam-constrained azapeptide inhibitors of human cathepsin K are described. Enhanced stability to proteolytic cleavage over acyclic analogues is discussed.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1999
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790254

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=790254